Product Information
TRETINOIN 0.1% CREAM is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.8316 per GM under NDC 00378808445. Its NADAC has been published 373 times since May 8, 2019.
Strength
1 mg/g
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378808445
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
TRETINOINApproval Type
Authorized Generic (NDA)
FDA Application
NDA017340On Market Since
2/27/2019
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.1% CREAM has been published 373 times since May 8, 2019, and over the history we have for it it has declined 74.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.8316 per GM |
|---|---|
| All-time high | $4.0182 (Jun 12, 2019) |
| All-time low | $0.8316 (Jun 17, 2026) |
| 52-week high | $1.2604 |
| 52-week low | $0.8316 |
| Median price | $2.2979 |
| Average price | $2.2000 |
| Largest weekly change | +41.6% (Jun 19, 2024) |
| Weeks tracked | 373 |
| Tracking since | May 8, 2019 |
Generic Alternatives
The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.1% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.1% CREAM, manufactured by Mylan Pharmaceuticals Inc., is $0.8316 per GM (NDC 00378808445), effective Jun 24, 2026.
How has the price of TRETINOIN 0.1% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.1% CREAM has declined 74.7%. It has been tracked across 373 weekly CMS publications since May 8, 2019.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.1% CREAM?
Since May 8, 2019, the NADAC for TRETINOIN 0.1% CREAM has ranged from a low of $0.8316 (Jun 17, 2026) to a high of $4.0182 (Jun 12, 2019), with a median of $2.2979 per GM.
Are there cheaper alternatives to TRETINOIN 0.1% CREAM?
6 NADAC-published products share the same active ingredient, strength, and dosage form as TRETINOIN 0.1% CREAM, but none are currently priced below it.
Who manufactures TRETINOIN 0.1% CREAM?
TRETINOIN 0.1% CREAM (NDC 00378808445) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.
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