Product Information
TRETINOIN 0.1% CREAM is a generic product labeled by NorthStar Rx LLC, priced at $0.7701 per GM under NDC 16714025002. Its NADAC has been published 213 times since Sep 7, 2022.
FDA first approved this application on Jan 22, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1 mg/g
Manufacturer
NorthStar Rx LLCNDC
16714025002
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA211645FDA Approved
1/22/2019
TE Code
AB
On Market Since
1/22/2019
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.1% CREAM has been published 213 times since Sep 7, 2022, and over the history we have for it it has declined 68.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.7701 per GM |
|---|---|
| All-time high | $2.6677 (Jul 12, 2023) |
| All-time low | $0.7625 (Aug 19, 2026) |
| 52-week high | $1.1272 |
| 52-week low | $0.7625 |
| Median price | $1.4719 |
| Average price | $1.6030 |
| Largest weekly change | +41.6% (Jun 19, 2024) |
| Weeks tracked | 213 |
| Tracking since | Sep 7, 2022 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
NorthStar Rx LLC manufacturer profile
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Drug market
Tretinoin market comparison
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Therapeutic class
Retinoid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.1% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.1% CREAM, manufactured by NorthStar Rx LLC, is $0.7701 per GM (NDC 16714025002), effective Sep 30, 2026.
How has the price of TRETINOIN 0.1% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.1% CREAM has declined 68.8%. It has been tracked across 213 weekly CMS publications since Sep 7, 2022.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.1% CREAM?
Since Sep 7, 2022, the NADAC for TRETINOIN 0.1% CREAM has ranged from a low of $0.7625 (Aug 19, 2026) to a high of $2.6677 (Jul 12, 2023), with a median of $1.4719 per GM.
Are there cheaper alternatives to TRETINOIN 0.1% CREAM?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TRETINOIN 0.1% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures TRETINOIN 0.1% CREAM?
TRETINOIN 0.1% CREAM (NDC 16714025002) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.