Product Information

TRETINOIN 0.1% CREAM is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.9748 per GM under NDC 00378808420. Its NADAC has been published 356 times since Sep 4, 2019.

TRETINOIN 0.1% CREAM

Tretinoin
$0.9748per GM

Strength

1 mg/g

NDC

00378808420

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

TRETINOIN

Approval Type

Authorized Generic (NDA)

FDA Application

NDA017340

On Market Since

2/27/2019

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for TRETINOIN 0.1% CREAM has been published 356 times since Sep 4, 2019, and over the history we have for it it has declined 79.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.9748 per GM
All-time high$4.8464 (Mar 11, 2020)
All-time low$0.9748 (Jun 17, 2026)
52-week high$1.5069
52-week low$0.9748
Median price$2.4873
Average price$2.6797
Largest weekly change-36.0% (Nov 20, 2024)
Weeks tracked356
Tracking sinceSep 4, 2019

Price History

1W

0.0%

1M

-4.1%

3M

-8.0%

6M

-8.2%

1Y

-35.3%

3Y

-62.3%

5Y

-73.4%

All

-79.5%

Generic Alternatives

The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 15% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of TRETINOIN 0.1% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.1% CREAM, manufactured by Mylan Pharmaceuticals Inc., is $0.9748 per GM (NDC 00378808420), effective Jun 24, 2026.

How has the price of TRETINOIN 0.1% CREAM changed over time?

Over the history we have for it, the NADAC for TRETINOIN 0.1% CREAM has declined 79.5%. It has been tracked across 356 weekly CMS publications since Sep 4, 2019.

What are the highest and lowest recorded NADAC prices for TRETINOIN 0.1% CREAM?

Since Sep 4, 2019, the NADAC for TRETINOIN 0.1% CREAM has ranged from a low of $0.9748 (Jun 17, 2026) to a high of $4.8464 (Mar 11, 2020), with a median of $2.4873 per GM.

Are there cheaper alternatives to TRETINOIN 0.1% CREAM?

Yes. 6 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, TRETINOIN 0.1% CREAM, is $0.8316 per GM — about 15% below TRETINOIN 0.1% CREAM.

Who manufactures TRETINOIN 0.1% CREAM?

TRETINOIN 0.1% CREAM (NDC 00378808420) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.