Product Information
ADAPALENE 0.1% CREAM is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $2.8545 per GM under NDC 45802045384. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on May 26, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.1 g/100g
Manufacturer
Padagis Israel Pharmaceuticals LtdNDC
45802045384
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
ADAPALENEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020748FDA Approved
5/26/2000
TE Code
AB
On Market Since
10/26/2010
Pharmacological Classes
Price Statistics
The NADAC for ADAPALENE 0.1% CREAM has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 25.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.8545 per GM |
|---|---|
| All-time high | $4.3508 (Jan 10, 2018) |
| All-time low | $2.2649 (Jul 17, 2024) |
| 52-week high | $2.8545 |
| 52-week low | $2.4342 |
| Median price | $3.5491 |
| Average price | $3.4433 |
| Largest weekly change | +31.1% (Feb 23, 2022) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Adapalene market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
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Manufacturer
Padagis Israel Pharmaceuticals Ltd manufacturer profile
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Drug market
Adapalene market comparison
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Therapeutic class
Retinoid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of ADAPALENE 0.1% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for ADAPALENE 0.1% CREAM, manufactured by Padagis Israel Pharmaceuticals Ltd, is $2.8545 per GM (NDC 45802045384), effective Sep 30, 2026.
How has the price of ADAPALENE 0.1% CREAM changed over time?
Over the history we have for it, the NADAC for ADAPALENE 0.1% CREAM has declined 25.9%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ADAPALENE 0.1% CREAM?
Since Nov 28, 2013, the NADAC for ADAPALENE 0.1% CREAM has ranged from a low of $2.2649 (Jul 17, 2024) to a high of $4.3508 (Jan 10, 2018), with a median of $3.5491 per GM.
Are there cheaper alternatives to ADAPALENE 0.1% CREAM?
No other NADAC-published product currently shares the active ingredient and strength of ADAPALENE 0.1% CREAM in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures ADAPALENE 0.1% CREAM?
ADAPALENE 0.1% CREAM (NDC 45802045384) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.