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Product Information

ADAPALENE 0.1% CREAM is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $2.4901 per GM under NDC 45802045384. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on May 26, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ADAPALENE 0.1% CREAM

Adapalene
$2.4901per GM

Strength

.1 g/100g

NDC

45802045384

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

ADAPALENE

Approval Type

Authorized Generic (NDA)

FDA Application

NDA020748

FDA Approved

5/26/2000

TE Code

AB

On Market Since

10/26/2010

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for ADAPALENE 0.1% CREAM has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 35.4%. The table below summarizes its recorded NADAC range and movement.

Current price$2.4901 per GM
All-time high$4.3508 (Jan 10, 2018)
All-time low$2.2649 (Jul 17, 2024)
52-week high$2.7014
52-week low$2.4342
Median price$3.5667
Average price$3.4508
Largest weekly change+31.1% (Feb 23, 2022)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-2.3%

1M

-2.3%

3M

-5.8%

6M

+1.7%

1Y

-7.8%

3Y

-22.8%

5Y

-34.3%

All

-35.4%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Adapalene market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Related Drugs

Same classification

ADAPALENE-BNZYL PEROX 0.1-2.5%
Generic
21922005250•Encube Ethicals, Inc.
$0.3288
per GM
ADAPALENE-BNZYL PEROX 0.1-2.5%
Generic
45802084601•Padagis Israel Pharmaceuticals Ltd
$0.3288
per GM
ADAPALENE-BNZYL PEROX 0.1-2.5%
Generic
51672136403•Sun Pharmaceutical Industries Inc.
$0.3288
per GM
ADAPALENE-BNZYL PEROX 0.1-2.5%
Generic
68462030147•Glenmark Pharmaceuticals Inc., USA
$0.3288
per GM
ADAPALENE 0.1% GEL
Generic
00536141226•Rugby Laboratories
$0.3380
per GM
ADAPALENE 0.1% GEL
Generic
00536141220•Rugby Laboratories
$0.4670
per GM
TRETINOIN 0.025% CREAM
Generic
00378808245•Mylan Pharmaceuticals Inc.
$0.4684
per GM
TRETINOIN 0.025% CREAM
Generic
00472011745•Actavis Pharma, Inc.
$0.4684
per GM
TRETINOIN 0.025% CREAM
Generic
00574222545•Padagis US LLC
$0.4684
per GM
TRETINOIN 0.025% CREAM
Generic
16714027002•NorthStar Rx LLC
$0.4684
per GM

Frequently asked questions

What is the NADAC price of ADAPALENE 0.1% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for ADAPALENE 0.1% CREAM, manufactured by Padagis Israel Pharmaceuticals Ltd, is $2.4901 per GM (NDC 45802045384), effective Aug 19, 2026.

How has the price of ADAPALENE 0.1% CREAM changed over time?

Over the history we have for it, the NADAC for ADAPALENE 0.1% CREAM has declined 35.4%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for ADAPALENE 0.1% CREAM?

Since Nov 28, 2013, the NADAC for ADAPALENE 0.1% CREAM has ranged from a low of $2.2649 (Jul 17, 2024) to a high of $4.3508 (Jan 10, 2018), with a median of $3.5667 per GM.

Are there cheaper alternatives to ADAPALENE 0.1% CREAM?

No other NADAC-published product currently shares the active ingredient and strength of ADAPALENE 0.1% CREAM in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures ADAPALENE 0.1% CREAM?

ADAPALENE 0.1% CREAM (NDC 45802045384) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.