Product Information
TRETINOIN 0.05% CREAM is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $1.5688 per GM under NDC 51672139400. Its NADAC has been published 392 times since Feb 20, 2019.
FDA first approved this application on Jan 25, 2019. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Sun Pharmaceutical Industries Inc.NDC
51672139400
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA211644FDA Approved
1/25/2019
TE Code
AB1
On Market Since
1/25/2019
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.05% CREAM has been published 392 times since Feb 20, 2019, and over the history we have for it it has declined 55.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.5688 per GM |
|---|---|
| All-time high | $3.7342 (Sep 11, 2019) |
| All-time low | $1.1766 (Nov 20, 2024) |
| 52-week high | $1.7000 |
| 52-week low | $1.5482 |
| Median price | $2.0391 |
| Average price | $2.3631 |
| Largest weekly change | +45.8% (Aug 21, 2024) |
| Weeks tracked | 392 |
| Tracking since | Feb 20, 2019 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 41% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRETINOIN 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.05% CREAM, manufactured by Sun Pharmaceutical Industries Inc., is $1.5688 per GM (NDC 51672139400), effective Aug 19, 2026.
How has the price of TRETINOIN 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.05% CREAM has declined 55.8%. It has been tracked across 392 weekly CMS publications since Feb 20, 2019.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.05% CREAM?
Since Feb 20, 2019, the NADAC for TRETINOIN 0.05% CREAM has ranged from a low of $1.1766 (Nov 20, 2024) to a high of $3.7342 (Sep 11, 2019), with a median of $2.0391 per GM.
Are there cheaper alternatives to TRETINOIN 0.05% CREAM?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TRETINOIN 0.05% CREAM, is $0.9284 per GM — about 41% below TRETINOIN 0.05% CREAM.
Who manufactures TRETINOIN 0.05% CREAM?
TRETINOIN 0.05% CREAM (NDC 51672139400) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.