Product Information
TRETINOIN 0.025% CREAM is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.5720 per GM under NDC 00378808220. Its NADAC has been published 364 times since Jul 10, 2019.
Strength
.25 mg/g
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378808220
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
TRETINOINApproval Type
Authorized Generic (NDA)
FDA Application
NDA019049On Market Since
4/3/2019
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.025% CREAM has been published 364 times since Jul 10, 2019, and over the history we have for it it has declined 75.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5720 per GM |
|---|---|
| All-time high | $2.6694 (Nov 11, 2020) |
| All-time low | $0.5720 (Jun 17, 2026) |
| 52-week high | $1.0981 |
| 52-week low | $0.5720 |
| Median price | $1.5301 |
| Average price | $1.6151 |
| Largest weekly change | +51.5% (Oct 21, 2020) |
| Weeks tracked | 364 |
| Tracking since | Jul 10, 2019 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 15% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.025% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.025% CREAM, manufactured by Mylan Pharmaceuticals Inc., is $0.5720 per GM (NDC 00378808220), effective Jun 24, 2026.
How has the price of TRETINOIN 0.025% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.025% CREAM has declined 75.9%. It has been tracked across 364 weekly CMS publications since Jul 10, 2019.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.025% CREAM?
Since Jul 10, 2019, the NADAC for TRETINOIN 0.025% CREAM has ranged from a low of $0.5720 (Jun 17, 2026) to a high of $2.6694 (Nov 11, 2020), with a median of $1.5301 per GM.
Are there cheaper alternatives to TRETINOIN 0.025% CREAM?
Yes. 5 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, TRETINOIN 0.025% CREAM, is $0.4851 per GM — about 15% below TRETINOIN 0.025% CREAM.
Who manufactures TRETINOIN 0.025% CREAM?
TRETINOIN 0.025% CREAM (NDC 00378808220) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.
Related Drugs
Same classification