Product Information
PROMETHEGAN 50 MG SUPPOSITORY is a generic product labeled by Cosette Pharmaceuticals, Inc., priced at $26.6913 per EA under NDC 00713013212. Its NADAC has been published 372 times since Nov 28, 2013.
FDA first approved this application on Aug 14, 1987.
The High Outlier badge above means this manufacturer's average price in the promethazine hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 mg/1
Manufacturer
Cosette Pharmaceuticals, Inc.NDC
00713013212
Classification
Generic
Dosage Form
SUPPOSITORY
Route
RECTAL
Effective Date
9/23/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA087165FDA Approved
8/14/1987
On Market Since
8/31/1987
Pharmacological Classes
Price Statistics
The NADAC for PROMETHEGAN 50 MG SUPPOSITORY has been published 372 times since Nov 28, 2013, and over the history we have for it it has risen 87.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $26.6913 per EA |
|---|---|
| All-time high | $31.0010 (Dec 13, 2017) |
| All-time low | $14.2081 (Nov 28, 2013) |
| 52-week high | $26.6913 |
| 52-week low | $24.4778 |
| Median price | $25.7531 |
| Average price | $25.6297 |
| Largest weekly change | +54.9% (Apr 23, 2014) |
| Weeks tracked | 372 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the promethazine hydrochloride market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Cosette Pharmaceuticals, Inc. manufacturer profile
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Drug market
promethazine hydrochloride market comparison
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Therapeutic class
Phenothiazine class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of PROMETHEGAN 50 MG SUPPOSITORY?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHEGAN 50 MG SUPPOSITORY, manufactured by Cosette Pharmaceuticals, Inc., is $26.6913 per EA (NDC 00713013212), effective Sep 30, 2026.
How has the price of PROMETHEGAN 50 MG SUPPOSITORY changed over time?
Over the history we have for it, the NADAC for PROMETHEGAN 50 MG SUPPOSITORY has risen 87.9%. It has been tracked across 372 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for PROMETHEGAN 50 MG SUPPOSITORY?
Since Nov 28, 2013, the NADAC for PROMETHEGAN 50 MG SUPPOSITORY has ranged from a low of $14.2081 (Nov 28, 2013) to a high of $31.0010 (Dec 13, 2017), with a median of $25.7531 per EA.
Are there cheaper alternatives to PROMETHEGAN 50 MG SUPPOSITORY?
No other NADAC-published product currently shares the active ingredient and strength of PROMETHEGAN 50 MG SUPPOSITORY in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures PROMETHEGAN 50 MG SUPPOSITORY?
PROMETHEGAN 50 MG SUPPOSITORY (NDC 00713013212) is labeled by Cosette Pharmaceuticals, Inc., and CMS classifies it as a generic product.