Product Information
PROMETHEGAN 50 MG SUPPOSITORY is a generic product labeled by Cosette Pharmaceuticals, Inc., priced at $24.5433 per EA under NDC 00713013212. Its NADAC has been published 358 times since Nov 28, 2013.
The High Outlier badge above means this manufacturer's average price in the promethazine hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 mg/1
Manufacturer
Cosette Pharmaceuticals, Inc.NDC
00713013212
Classification
Generic
Dosage Form
SUPPOSITORY
Route
RECTAL
Last Updated
3/18/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA087165On Market Since
8/31/1987
Pharmacological Classes
Price Statistics
The NADAC for PROMETHEGAN 50 MG SUPPOSITORY has been published 358 times since Nov 28, 2013, and over the history we have for it it has risen 72.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $24.5433 per EA |
|---|---|
| All-time high | $31.0010 (Dec 13, 2017) |
| All-time low | $14.2081 (Nov 28, 2013) |
| 52-week high | $26.4064 |
| 52-week low | $24.4778 |
| Median price | $25.8226 |
| Average price | $25.6602 |
| Largest weekly change | +54.9% (Apr 23, 2014) |
| Weeks tracked | 358 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 100% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of PROMETHEGAN 50 MG SUPPOSITORY?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHEGAN 50 MG SUPPOSITORY, manufactured by Cosette Pharmaceuticals, Inc., is $24.5433 per EA (NDC 00713013212), effective Jun 24, 2026.
How has the price of PROMETHEGAN 50 MG SUPPOSITORY changed over time?
Over the history we have for it, the NADAC for PROMETHEGAN 50 MG SUPPOSITORY has risen 72.7%. It has been tracked across 358 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for PROMETHEGAN 50 MG SUPPOSITORY?
Since Nov 28, 2013, the NADAC for PROMETHEGAN 50 MG SUPPOSITORY has ranged from a low of $14.2081 (Nov 28, 2013) to a high of $31.0010 (Dec 13, 2017), with a median of $25.8226 per EA.
Are there cheaper alternatives to PROMETHEGAN 50 MG SUPPOSITORY?
Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, PROMETHAZINE 50 MG TABLET, is $0.0815 per EA — about 100% below PROMETHEGAN 50 MG SUPPOSITORY.
Who manufactures PROMETHEGAN 50 MG SUPPOSITORY?
PROMETHEGAN 50 MG SUPPOSITORY (NDC 00713013212) is labeled by Cosette Pharmaceuticals, Inc., and CMS classifies it as a generic product.
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Same classification