Product Information
PROMETHAZINE 6.25 MG/5 ML SOLN is a generic product labeled by Chartwell RX LLC, priced at $0.0420 per ML under NDC 62135077447. Its NADAC has been published 134 times since Mar 13, 2024.
FDA first approved this application on Sep 25, 1998. Its Orange Book therapeutic-equivalence code is AA.
Strength
6.25 mg/5mL
Manufacturer
Chartwell RX LLCNDC
62135077447
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040026FDA Approved
9/25/1998
TE Code
AA
On Market Since
9/25/1998
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE 6.25 MG/5 ML SOLN has been published 134 times since Mar 13, 2024, and over the history we have for it it has risen 16.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0420 per ML |
|---|---|
| All-time high | $0.0446 (Nov 12, 2025) |
| All-time low | $0.0308 (May 22, 2024) |
| 52-week high | $0.0446 |
| 52-week low | $0.0410 |
| Median price | $0.0409 |
| Average price | $0.0393 |
| Largest weekly change | -17.6% (May 22, 2024) |
| Weeks tracked | 134 |
| Tracking since | Mar 13, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Chartwell RX LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
PROMETHAZINE HYDROCHLORIDE market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Phenothiazine class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of PROMETHAZINE 6.25 MG/5 ML SOLN?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 6.25 MG/5 ML SOLN, manufactured by Chartwell RX LLC, is $0.0420 per ML (NDC 62135077447), effective Sep 30, 2026.
How has the price of PROMETHAZINE 6.25 MG/5 ML SOLN changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE 6.25 MG/5 ML SOLN has risen 16.7%. It has been tracked across 134 weekly CMS publications since Mar 13, 2024.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE 6.25 MG/5 ML SOLN?
Since Mar 13, 2024, the NADAC for PROMETHAZINE 6.25 MG/5 ML SOLN has ranged from a low of $0.0308 (May 22, 2024) to a high of $0.0446 (Nov 12, 2025), with a median of $0.0409 per ML.
Are there cheaper alternatives to PROMETHAZINE 6.25 MG/5 ML SOLN?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, PROMETHAZINE 6.25 MG/5 ML SOLN, is $0.0410 per ML — about 2% below PROMETHAZINE 6.25 MG/5 ML SOLN.
Who manufactures PROMETHAZINE 6.25 MG/5 ML SOLN?
PROMETHAZINE 6.25 MG/5 ML SOLN (NDC 62135077447) is labeled by Chartwell RX LLC, and CMS classifies it as a generic product.