Product Information
PROMETHAZINE 6.25 MG/5 ML SOLN is a generic product labeled by Chartwell RX LLC, priced at $0.0422 per ML under NDC 62135077447. Its NADAC has been published 128 times since Mar 13, 2024.
FDA first approved this application on Sep 25, 1998. Its Orange Book therapeutic-equivalence code is AA.
Strength
6.25 mg/5mL
Manufacturer
Chartwell RX LLCNDC
62135077447
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040026FDA Approved
9/25/1998
TE Code
AA
On Market Since
9/25/1998
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE 6.25 MG/5 ML SOLN has been published 128 times since Mar 13, 2024, and over the history we have for it it has risen 17.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0422 per ML |
|---|---|
| All-time high | $0.0446 (Nov 12, 2025) |
| All-time low | $0.0308 (May 22, 2024) |
| 52-week high | $0.0446 |
| 52-week low | $0.0410 |
| Median price | $0.0406 |
| Average price | $0.0391 |
| Largest weekly change | -17.6% (May 22, 2024) |
| Weeks tracked | 128 |
| Tracking since | Mar 13, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PROMETHAZINE 6.25 MG/5 ML SOLN?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 6.25 MG/5 ML SOLN, manufactured by Chartwell RX LLC, is $0.0422 per ML (NDC 62135077447), effective Aug 19, 2026.
How has the price of PROMETHAZINE 6.25 MG/5 ML SOLN changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE 6.25 MG/5 ML SOLN has risen 17.3%. It has been tracked across 128 weekly CMS publications since Mar 13, 2024.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE 6.25 MG/5 ML SOLN?
Since Mar 13, 2024, the NADAC for PROMETHAZINE 6.25 MG/5 ML SOLN has ranged from a low of $0.0308 (May 22, 2024) to a high of $0.0446 (Nov 12, 2025), with a median of $0.0406 per ML.
Are there cheaper alternatives to PROMETHAZINE 6.25 MG/5 ML SOLN?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, PROMETHAZINE 6.25 MG/5 ML SOLN, is $0.0410 per ML — about 3% below PROMETHAZINE 6.25 MG/5 ML SOLN.
Who manufactures PROMETHAZINE 6.25 MG/5 ML SOLN?
PROMETHAZINE 6.25 MG/5 ML SOLN (NDC 62135077447) is labeled by Chartwell RX LLC, and CMS classifies it as a generic product.