Product Information
PROMETHAZINE 6.25 MG/5 ML SOLN is a generic product labeled by Nostrum Laboratories, Inc., priced at $0.0410 per ML under NDC 29033050034. Its NADAC has been published 43 times since Dec 11, 2024.
FDA first approved this application on Mar 13, 2009. Its Orange Book therapeutic-equivalence code is AA.
Strength
6.25 mg/5mL
Manufacturer
Nostrum Laboratories, Inc.NDC
29033050034
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
9/17/2025
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040891FDA Approved
3/13/2009
TE Code
AA
On Market Since
7/18/2024
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE 6.25 MG/5 ML SOLN has been published 43 times since Dec 11, 2024, and over the history we have for it it has risen 9.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0410 per ML |
|---|---|
| All-time high | $0.0414 (Jul 16, 2025) |
| All-time low | $0.0369 (Dec 18, 2024) |
| Median price | $0.0406 |
| Average price | $0.0396 |
| Largest weekly change | +3.4% (Mar 19, 2025) |
| Weeks tracked | 43 |
| Tracking since | Dec 11, 2024 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
N/A
5Y
N/A
All
+9.5%
Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Nostrum Laboratories, Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
PROMETHAZINE HYDROCHLORIDE market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Phenothiazine class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of PROMETHAZINE 6.25 MG/5 ML SOLN?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 6.25 MG/5 ML SOLN, manufactured by Nostrum Laboratories, Inc., is $0.0410 per ML (NDC 29033050034), effective Oct 1, 2025.
How has the price of PROMETHAZINE 6.25 MG/5 ML SOLN changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE 6.25 MG/5 ML SOLN has risen 9.5%. It has been tracked across 43 weekly CMS publications since Dec 11, 2024.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE 6.25 MG/5 ML SOLN?
Since Dec 11, 2024, the NADAC for PROMETHAZINE 6.25 MG/5 ML SOLN has ranged from a low of $0.0369 (Dec 18, 2024) to a high of $0.0414 (Jul 16, 2025), with a median of $0.0406 per ML.
Are there cheaper alternatives to PROMETHAZINE 6.25 MG/5 ML SOLN?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as PROMETHAZINE 6.25 MG/5 ML SOLN in a comparable dosage form, but none are currently priced below it.
Who manufactures PROMETHAZINE 6.25 MG/5 ML SOLN?
PROMETHAZINE 6.25 MG/5 ML SOLN (NDC 29033050034) is labeled by Nostrum Laboratories, Inc., and CMS classifies it as a generic product.