Product Information
PROMETHEGAN 12.5 MG SUPPOS is a generic product labeled by Cosette Pharmaceuticals, Inc., priced at $2.0372 per EA under NDC 00713053612. Its NADAC has been published 657 times since Nov 28, 2013.
The High Outlier badge above means this manufacturer's average price in the promethazine hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
12.5 mg/1
Manufacturer
Cosette Pharmaceuticals, Inc.NDC
00713053612
Classification
Generic
Dosage Form
SUPPOSITORY
Route
RECTAL
Last Updated
6/17/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040428On Market Since
2/28/2004
Pharmacological Classes
Price Statistics
The NADAC for PROMETHEGAN 12.5 MG SUPPOS has been published 657 times since Nov 28, 2013, and over the history we have for it it has declined 78.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.0372 per EA |
|---|---|
| All-time high | $10.4335 (Jul 15, 2015) |
| All-time low | $1.6445 (Nov 20, 2024) |
| 52-week high | $2.4682 |
| 52-week low | $1.7078 |
| Median price | $5.5019 |
| Average price | $5.6541 |
| Largest weekly change | +60.0% (Jan 18, 2023) |
| Weeks tracked | 657 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 98% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of PROMETHEGAN 12.5 MG SUPPOS?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHEGAN 12.5 MG SUPPOS, manufactured by Cosette Pharmaceuticals, Inc., is $2.0372 per EA (NDC 00713053612), effective Jun 24, 2026.
How has the price of PROMETHEGAN 12.5 MG SUPPOS changed over time?
Over the history we have for it, the NADAC for PROMETHEGAN 12.5 MG SUPPOS has declined 78.2%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for PROMETHEGAN 12.5 MG SUPPOS?
Since Nov 28, 2013, the NADAC for PROMETHEGAN 12.5 MG SUPPOS has ranged from a low of $1.6445 (Nov 20, 2024) to a high of $10.4335 (Jul 15, 2015), with a median of $5.5019 per EA.
Are there cheaper alternatives to PROMETHEGAN 12.5 MG SUPPOS?
Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, PROMETHAZINE 12.5 MG TABLET, is $0.0418 per EA — about 98% below PROMETHEGAN 12.5 MG SUPPOS.
Who manufactures PROMETHEGAN 12.5 MG SUPPOS?
PROMETHEGAN 12.5 MG SUPPOS (NDC 00713053612) is labeled by Cosette Pharmaceuticals, Inc., and CMS classifies it as a generic product.
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Same classification