This NDC is on FDA's drug shortage list (posted Nov 21, 2023)
Product Information
PROMETHAZINE 25 MG/ML AMPUL is a generic product labeled by XGen Pharmaceuticals DJB, Inc., priced at $1.3133 per ML under NDC 39822552503. Its NADAC has been published 170 times since Sep 22, 2021.
FDA first approved this application on Apr 24, 2008. Its Orange Book therapeutic-equivalence code is AP.
Strength
25 mg/mL
Manufacturer
XGen Pharmaceuticals DJB, Inc.NDC
39822552503
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
8/19/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040737FDA Approved
4/24/2008
TE Code
AP
On Market Since
1/30/2015
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE 25 MG/ML AMPUL has been published 170 times since Sep 22, 2021, and over the history we have for it it has declined 26.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.3133 per ML |
|---|---|
| All-time high | $1.7806 (Sep 14, 2022) |
| All-time low | $1.2697 (Jul 22, 2026) |
| 52-week high | $1.6534 |
| 52-week low | $1.2697 |
| Median price | $1.6049 |
| Average price | $1.5976 |
| Largest weekly change | -11.8% (May 22, 2024) |
| Weeks tracked | 170 |
| Tracking since | Sep 22, 2021 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the PROMETHAZINE HYDROCHLORIDE market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PROMETHAZINE 25 MG/ML AMPUL?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 25 MG/ML AMPUL, manufactured by XGen Pharmaceuticals DJB, Inc., is $1.3133 per ML (NDC 39822552503), effective Aug 19, 2026.
How has the price of PROMETHAZINE 25 MG/ML AMPUL changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE 25 MG/ML AMPUL has declined 26.2%. It has been tracked across 170 weekly CMS publications since Sep 22, 2021.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE 25 MG/ML AMPUL?
Since Sep 22, 2021, the NADAC for PROMETHAZINE 25 MG/ML AMPUL has ranged from a low of $1.2697 (Jul 22, 2026) to a high of $1.7806 (Sep 14, 2022), with a median of $1.6049 per ML.
Are there cheaper alternatives to PROMETHAZINE 25 MG/ML AMPUL?
No other NADAC-published product currently shares the active ingredient and strength of PROMETHAZINE 25 MG/ML AMPUL in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures PROMETHAZINE 25 MG/ML AMPUL?
PROMETHAZINE 25 MG/ML AMPUL (NDC 39822552503) is labeled by XGen Pharmaceuticals DJB, Inc., and CMS classifies it as a generic product.
Is PROMETHAZINE 25 MG/ML AMPUL in shortage?
Yes — NDC 39822552503 is currently listed in FDA's drug shortage database (posted Nov 21, 2023).