Product Information

PROMETHAZINE 6.25 MG/5 ML SYRP is a generic product labeled by Cranbury Pharmaceuticals, LLC, priced at $0.0422 per ML under NDC 27808005102. Its NADAC has been published 217 times since Jun 29, 2022.

FDA first approved this application on Jun 28, 2012. Its Orange Book therapeutic-equivalence code is AA.

PROMETHAZINE 6.25 MG/5 ML SYRP

promethazine hydrochloride
$0.0422per ML

Strength

6.25 mg/5mL

NDC

27808005102

Classification

Generic

Dosage Form

SYRUP

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

PROMETHAZINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA091675

FDA Approved

6/28/2012

TE Code

AA

On Market Since

6/8/2012

Pharmacological Classes

Phenothiazine
Phenothiazines

Price Statistics

The NADAC for PROMETHAZINE 6.25 MG/5 ML SYRP has been published 217 times since Jun 29, 2022, and over the history we have for it it has declined 7.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0422 per ML
All-time high$0.0458 (Jul 13, 2022)
All-time low$0.0262 (Sep 20, 2023)
52-week high$0.0446
52-week low$0.0410
Median price$0.0374
Average price$0.0364
Largest weekly change-26.1% (Dec 21, 2022)
Weeks tracked217
Tracking sinceJun 29, 2022

Price History

1W

+1.3%

1M

+1.3%

3M

+1.5%

6M

+0.5%

1Y

+2.2%

3Y

+31.1%

5Y

N/A

All

-7.8%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROMETHAZINE 6.25 MG/5 ML SYRP?

The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 6.25 MG/5 ML SYRP, manufactured by Cranbury Pharmaceuticals, LLC, is $0.0422 per ML (NDC 27808005102), effective Aug 19, 2026.

How has the price of PROMETHAZINE 6.25 MG/5 ML SYRP changed over time?

Over the history we have for it, the NADAC for PROMETHAZINE 6.25 MG/5 ML SYRP has declined 7.8%. It has been tracked across 217 weekly CMS publications since Jun 29, 2022.

What are the highest and lowest recorded NADAC prices for PROMETHAZINE 6.25 MG/5 ML SYRP?

Since Jun 29, 2022, the NADAC for PROMETHAZINE 6.25 MG/5 ML SYRP has ranged from a low of $0.0262 (Sep 20, 2023) to a high of $0.0458 (Jul 13, 2022), with a median of $0.0374 per ML.

Are there cheaper alternatives to PROMETHAZINE 6.25 MG/5 ML SYRP?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as PROMETHAZINE 6.25 MG/5 ML SYRP in a comparable dosage form, but none are currently priced below it.

Who manufactures PROMETHAZINE 6.25 MG/5 ML SYRP?

PROMETHAZINE 6.25 MG/5 ML SYRP (NDC 27808005102) is labeled by Cranbury Pharmaceuticals, LLC, and CMS classifies it as a generic product.