Product Information
PROMETHAZINE 6.25 MG/5 ML SYRP is a generic product labeled by Xttrium Laboratories, Inc., priced at $0.0418 per ML under NDC 00116402316. Its NADAC has been published 53 times since Jun 25, 2025.
Strength
6.25 mg/5mL
Manufacturer
Xttrium Laboratories, Inc.NDC
00116402316
Classification
Generic
Dosage Form
SYRUP
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA087953On Market Since
4/7/2025
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE 6.25 MG/5 ML SYRP has been published 53 times since Jun 25, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0418 per ML |
|---|---|
| All-time high | $0.0446 (Nov 12, 2025) |
| All-time low | $0.0406 (Jul 23, 2025) |
| 52-week high | $0.0446 |
| 52-week low | $0.0406 |
| Median price | $0.0416 |
| Average price | $0.0422 |
| Largest weekly change | +8.9% (Oct 22, 2025) |
| Weeks tracked | 53 |
| Tracking since | Jun 25, 2025 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of PROMETHAZINE 6.25 MG/5 ML SYRP?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 6.25 MG/5 ML SYRP, manufactured by Xttrium Laboratories, Inc., is $0.0418 per ML (NDC 00116402316), effective Jun 24, 2026.
How has the price of PROMETHAZINE 6.25 MG/5 ML SYRP changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE 6.25 MG/5 ML SYRP has held within roughly two percent of its current level. It has been tracked across 53 weekly CMS publications since Jun 25, 2025.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE 6.25 MG/5 ML SYRP?
Since Jun 25, 2025, the NADAC for PROMETHAZINE 6.25 MG/5 ML SYRP has ranged from a low of $0.0406 (Jul 23, 2025) to a high of $0.0446 (Nov 12, 2025), with a median of $0.0416 per ML.
Are there cheaper alternatives to PROMETHAZINE 6.25 MG/5 ML SYRP?
1 NADAC-published product shares the same active ingredient, strength, and dosage form as PROMETHAZINE 6.25 MG/5 ML SYRP, but none are currently priced below it.
Who manufactures PROMETHAZINE 6.25 MG/5 ML SYRP?
PROMETHAZINE 6.25 MG/5 ML SYRP (NDC 00116402316) is labeled by Xttrium Laboratories, Inc., and CMS classifies it as a generic product.
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