Product Information
TRETINOIN 0.025% CREAM is a generic product labeled by Alembic Pharmaceuticals Inc., priced at $0.5529 per GM under NDC 62332080920. Its NADAC has been published 44 times since Dec 3, 2025.
FDA first approved this application on Aug 14, 2025. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.25 mg/g
Manufacturer
Alembic Pharmaceuticals Inc.NDC
62332080920
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA218399FDA Approved
8/14/2025
TE Code
AB
On Market Since
8/16/2025
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.025% CREAM has been published 44 times since Dec 3, 2025, and over the history we have for it it has declined 46.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5529 per GM |
|---|---|
| All-time high | $1.0282 (Dec 10, 2025) |
| All-time low | $0.5529 (Sep 23, 2026) |
| 52-week high | $1.0282 |
| 52-week low | $0.5529 |
| Median price | $0.7509 |
| Average price | $0.7659 |
| Largest weekly change | -16.1% (May 20, 2026) |
| Weeks tracked | 44 |
| Tracking since | Dec 3, 2025 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 17% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Alembic Pharmaceuticals Inc. manufacturer profile
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Drug market
Tretinoin market comparison
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Therapeutic class
Retinoid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.025% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.025% CREAM, manufactured by Alembic Pharmaceuticals Inc., is $0.5529 per GM (NDC 62332080920), effective Sep 30, 2026.
How has the price of TRETINOIN 0.025% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.025% CREAM has declined 46.2%. It has been tracked across 44 weekly CMS publications since Dec 3, 2025.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.025% CREAM?
Since Dec 3, 2025, the NADAC for TRETINOIN 0.025% CREAM has ranged from a low of $0.5529 (Sep 23, 2026) to a high of $1.0282 (Dec 10, 2025), with a median of $0.7509 per GM.
Are there cheaper alternatives to TRETINOIN 0.025% CREAM?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TRETINOIN 0.025% CREAM, is $0.4593 per GM — about 17% below TRETINOIN 0.025% CREAM.
Who manufactures TRETINOIN 0.025% CREAM?
TRETINOIN 0.025% CREAM (NDC 62332080920) is labeled by Alembic Pharmaceuticals Inc., and CMS classifies it as a generic product.