Product Information
PROMETHAZINE 25 MG/ML VIAL is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $1.7558 per ML under NDC 00641095525. Its NADAC has been published 474 times since Nov 28, 2013.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AP.
Strength
25 mg/mL
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00641095525
Classification
Generic
Dosage Form
INJECTION
Route
INTRAMUSCULAR; INTRAVENOUS
Effective Date
8/19/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA083312FDA Approved
Before 1982
TE Code
AP
On Market Since
9/19/1973
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE 25 MG/ML VIAL has been published 474 times since Nov 28, 2013, and over the history we have for it it has risen 127.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.7558 per ML |
|---|---|
| All-time high | $1.7691 (Apr 15, 2026) |
| All-time low | $0.7726 (Nov 28, 2013) |
| 52-week high | $1.7691 |
| 52-week low | $1.7316 |
| Median price | $1.0862 |
| Average price | $1.2364 |
| Largest weekly change | +63.9% (Mar 17, 2021) |
| Weeks tracked | 474 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 25% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PROMETHAZINE 25 MG/ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 25 MG/ML VIAL, manufactured by Hikma Pharmaceuticals USA Inc., is $1.7558 per ML (NDC 00641095525), effective Aug 19, 2026.
How has the price of PROMETHAZINE 25 MG/ML VIAL changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE 25 MG/ML VIAL has risen 127.3%. It has been tracked across 474 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE 25 MG/ML VIAL?
Since Nov 28, 2013, the NADAC for PROMETHAZINE 25 MG/ML VIAL has ranged from a low of $0.7726 (Nov 28, 2013) to a high of $1.7691 (Apr 15, 2026), with a median of $1.0862 per ML.
Are there cheaper alternatives to PROMETHAZINE 25 MG/ML VIAL?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, PROMETHAZINE 25 MG/ML AMPUL, is $1.3133 per ML — about 25% below PROMETHAZINE 25 MG/ML VIAL.
Who manufactures PROMETHAZINE 25 MG/ML VIAL?
PROMETHAZINE 25 MG/ML VIAL (NDC 00641095525) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.