Product Information

PROMETHAZINE 25 MG/ML VIAL is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $1.7541 per ML under NDC 00641620825. Its NADAC has been published 223 times since Jul 25, 2018.

PROMETHAZINE 25 MG/ML VIAL

Promethazine Hydrochloride
$1.7541per ML

Strength

25 mg/mL

NDC

00641620825

Classification

Generic

Dosage Form

INJECTION

Route

INTRAMUSCULAR; INTRAVENOUS

Last Updated

6/17/2026

Active Ingredients

PROMETHAZINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA083312

On Market Since

9/19/1973

Pharmacological Classes

Phenothiazine
Phenothiazines

Price Statistics

The NADAC for PROMETHAZINE 25 MG/ML VIAL has been published 223 times since Jul 25, 2018, and over the history we have for it it has risen 61.5%. The table below summarizes its recorded NADAC range and movement.

Current price$1.7541 per ML
All-time high$1.7691 (Apr 15, 2026)
All-time low$1.0267 (Sep 19, 2018)
52-week high$1.7691
52-week low$1.7245
Median price$1.6831
Average price$1.5304
Largest weekly change+63.9% (Mar 17, 2021)
Weeks tracked223
Tracking sinceJul 25, 2018

Price History

1W

0.0%

1M

+0.0%

3M

-0.9%

6M

+1.3%

1Y

+1.7%

3Y

+4.2%

5Y

+4.2%

All

+61.5%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 18% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 18%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of PROMETHAZINE 25 MG/ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 25 MG/ML VIAL, manufactured by Hikma Pharmaceuticals USA Inc., is $1.7541 per ML (NDC 00641620825), effective Jun 24, 2026.

How has the price of PROMETHAZINE 25 MG/ML VIAL changed over time?

Over the history we have for it, the NADAC for PROMETHAZINE 25 MG/ML VIAL has risen 61.5%. It has been tracked across 223 weekly CMS publications since Jul 25, 2018.

What are the highest and lowest recorded NADAC prices for PROMETHAZINE 25 MG/ML VIAL?

Since Jul 25, 2018, the NADAC for PROMETHAZINE 25 MG/ML VIAL has ranged from a low of $1.0267 (Sep 19, 2018) to a high of $1.7691 (Apr 15, 2026), with a median of $1.6831 per ML.

Are there cheaper alternatives to PROMETHAZINE 25 MG/ML VIAL?

Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, PROMETHAZINE 25 MG/ML AMPUL, is $1.4402 per ML — about 18% below PROMETHAZINE 25 MG/ML VIAL.

Who manufactures PROMETHAZINE 25 MG/ML VIAL?

PROMETHAZINE 25 MG/ML VIAL (NDC 00641620825) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.