Product Information
METHOTREXATE 2.5 MG TABLET is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.1635 per EA under NDC 68382077501. Its NADAC has been published 481 times since Apr 12, 2017.
Strength
2.5 mg/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382077501
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
METHOTREXATEApproval Type
Generic (ANDA)
FDA Application
ANDA207812On Market Since
2/9/2017
Pharmacological Classes
Price Statistics
The NADAC for METHOTREXATE 2.5 MG TABLET has been published 481 times since Apr 12, 2017, and over the history we have for it it has declined 85.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1635 per EA |
|---|---|
| All-time high | $1.1166 (Apr 12, 2017) |
| All-time low | $0.1507 (May 22, 2024) |
| 52-week high | $0.1694 |
| 52-week low | $0.1530 |
| Median price | $0.3019 |
| Average price | $0.4112 |
| Largest weekly change | +41.4% (Jun 19, 2024) |
| Weeks tracked | 481 |
| Tracking since | Apr 12, 2017 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of METHOTREXATE 2.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 2.5 MG TABLET, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.1635 per EA (NDC 68382077501), effective Jun 24, 2026.
How has the price of METHOTREXATE 2.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for METHOTREXATE 2.5 MG TABLET has declined 85.4%. It has been tracked across 481 weekly CMS publications since Apr 12, 2017.
What are the highest and lowest recorded NADAC prices for METHOTREXATE 2.5 MG TABLET?
Since Apr 12, 2017, the NADAC for METHOTREXATE 2.5 MG TABLET has ranged from a low of $0.1507 (May 22, 2024) to a high of $1.1166 (Apr 12, 2017), with a median of $0.3019 per EA.
Are there cheaper alternatives to METHOTREXATE 2.5 MG TABLET?
5 NADAC-published products share the same active ingredient, strength, and dosage form as METHOTREXATE 2.5 MG TABLET, but none are currently priced below it.
Who manufactures METHOTREXATE 2.5 MG TABLET?
METHOTREXATE 2.5 MG TABLET (NDC 68382077501) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.
Related Drugs
Same classification