Product Information
PROMETHAZINE 12.5 MG TABLET is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $0.0534 per EA under NDC 53746074501. Its NADAC has been published 202 times since Oct 12, 2022.
FDA first approved this application on Dec 13, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
12.5 mg/1
Manufacturer
Amneal Pharmaceuticals of New York LLCNDC
53746074501
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA091179FDA Approved
12/13/2010
TE Code
AB
On Market Since
6/22/2022
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE 12.5 MG TABLET has been published 202 times since Oct 12, 2022, and over the history we have for it it has risen 14.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0534 per EA |
|---|---|
| All-time high | $0.0563 (Oct 16, 2024) |
| All-time low | $0.0312 (Nov 20, 2024) |
| 52-week high | $0.0538 |
| 52-week low | $0.0477 |
| Median price | $0.0498 |
| Average price | $0.0483 |
| Largest weekly change | -37.5% (Nov 20, 2024) |
| Weeks tracked | 202 |
| Tracking since | Oct 12, 2022 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PROMETHAZINE 12.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 12.5 MG TABLET, manufactured by Amneal Pharmaceuticals of New York LLC, is $0.0534 per EA (NDC 53746074501), effective Aug 19, 2026.
How has the price of PROMETHAZINE 12.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE 12.5 MG TABLET has risen 14.3%. It has been tracked across 202 weekly CMS publications since Oct 12, 2022.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE 12.5 MG TABLET?
Since Oct 12, 2022, the NADAC for PROMETHAZINE 12.5 MG TABLET has ranged from a low of $0.0312 (Nov 20, 2024) to a high of $0.0563 (Oct 16, 2024), with a median of $0.0498 per EA.
Are there cheaper alternatives to PROMETHAZINE 12.5 MG TABLET?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROMETHAZINE 12.5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures PROMETHAZINE 12.5 MG TABLET?
PROMETHAZINE 12.5 MG TABLET (NDC 53746074501) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.