Product Information
PROMETHEGAN 25 MG SUPPOSITORY is a generic product labeled by Cosette Pharmaceuticals, Inc., priced at $2.0065 per EA under NDC 00713052612. Its NADAC has been published 657 times since Nov 28, 2013.
The High Outlier badge above means this manufacturer's average price in the Promethazine Hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
25 mg/1
Manufacturer
Cosette Pharmaceuticals, Inc.NDC
00713052612
Classification
Generic
Dosage Form
SUPPOSITORY
Route
RECTAL
Last Updated
6/17/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040428On Market Since
2/28/2002
Pharmacological Classes
Price Statistics
The NADAC for PROMETHEGAN 25 MG SUPPOSITORY has been published 657 times since Nov 28, 2013, and over the history we have for it it has declined 75.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.0065 per EA |
|---|---|
| All-time high | $9.2294 (May 13, 2015) |
| All-time low | $1.8394 (Nov 20, 2024) |
| 52-week high | $2.1721 |
| 52-week low | $1.8404 |
| Median price | $4.9195 |
| Average price | $5.2281 |
| Largest weekly change | +42.4% (Jul 19, 2023) |
| Weeks tracked | 657 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 10 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 10 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 98% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of PROMETHEGAN 25 MG SUPPOSITORY?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHEGAN 25 MG SUPPOSITORY, manufactured by Cosette Pharmaceuticals, Inc., is $2.0065 per EA (NDC 00713052612), effective Jun 24, 2026.
How has the price of PROMETHEGAN 25 MG SUPPOSITORY changed over time?
Over the history we have for it, the NADAC for PROMETHEGAN 25 MG SUPPOSITORY has declined 75.9%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for PROMETHEGAN 25 MG SUPPOSITORY?
Since Nov 28, 2013, the NADAC for PROMETHEGAN 25 MG SUPPOSITORY has ranged from a low of $1.8394 (Nov 20, 2024) to a high of $9.2294 (May 13, 2015), with a median of $4.9195 per EA.
Are there cheaper alternatives to PROMETHEGAN 25 MG SUPPOSITORY?
Yes. 10 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, PROMETHAZINE 25 MG TABLET, is $0.0462 per EA — about 98% below PROMETHEGAN 25 MG SUPPOSITORY.
Who manufactures PROMETHEGAN 25 MG SUPPOSITORY?
PROMETHEGAN 25 MG SUPPOSITORY (NDC 00713052612) is labeled by Cosette Pharmaceuticals, Inc., and CMS classifies it as a generic product.
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