Product Information

PROMETHAZINE 25 MG SUPPOSITORY is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $2.0065 per EA under NDC 45802075930. Its NADAC has been published 657 times since Nov 28, 2013.

PROMETHAZINE 25 MG SUPPOSITORY

Promethazine Hydrochloride
$2.0065per EA

Strength

25 mg/1

NDC

45802075930

Classification

Generic

Dosage Form

SUPPOSITORY

Route

RECTAL

Last Updated

6/17/2026

Active Ingredients

PROMETHAZINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA040500

On Market Since

5/17/2006

Pharmacological Classes

Phenothiazine
Phenothiazines

Price Statistics

The NADAC for PROMETHAZINE 25 MG SUPPOSITORY has been published 657 times since Nov 28, 2013, and over the history we have for it it has declined 75.9%. The table below summarizes its recorded NADAC range and movement.

Current price$2.0065 per EA
All-time high$9.2294 (May 13, 2015)
All-time low$1.8394 (Nov 20, 2024)
52-week high$2.1721
52-week low$1.8404
Median price$4.9195
Average price$5.2281
Largest weekly change+42.4% (Jul 19, 2023)
Weeks tracked657
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

+4.0%

3M

+2.5%

6M

-3.9%

1Y

-7.6%

3Y

-11.4%

5Y

-57.7%

All

-75.9%

Generic Alternatives

The matcher finds 9 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 9 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 98% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROMETHAZINE 25 MG SUPPOSITORY?

The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 25 MG SUPPOSITORY, manufactured by Padagis Israel Pharmaceuticals Ltd, is $2.0065 per EA (NDC 45802075930), effective Jun 24, 2026.

How has the price of PROMETHAZINE 25 MG SUPPOSITORY changed over time?

Over the history we have for it, the NADAC for PROMETHAZINE 25 MG SUPPOSITORY has declined 75.9%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for PROMETHAZINE 25 MG SUPPOSITORY?

Since Nov 28, 2013, the NADAC for PROMETHAZINE 25 MG SUPPOSITORY has ranged from a low of $1.8394 (Nov 20, 2024) to a high of $9.2294 (May 13, 2015), with a median of $4.9195 per EA.

Are there cheaper alternatives to PROMETHAZINE 25 MG SUPPOSITORY?

Yes. 9 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, PROMETHAZINE 25 MG TABLET, is $0.0462 per EA — about 98% below PROMETHAZINE 25 MG SUPPOSITORY.

Who manufactures PROMETHAZINE 25 MG SUPPOSITORY?

PROMETHAZINE 25 MG SUPPOSITORY (NDC 45802075930) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.