Product Information
PROMETHAZINE 12.5 MG SUPPOS is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $2.0372 per EA under NDC 45802075830. Its NADAC has been published 657 times since Nov 28, 2013.
Strength
12.5 mg/1
Manufacturer
Padagis Israel Pharmaceuticals LtdNDC
45802075830
Classification
Generic
Dosage Form
SUPPOSITORY
Route
RECTAL
Last Updated
6/17/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040500On Market Since
6/27/2006
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE 12.5 MG SUPPOS has been published 657 times since Nov 28, 2013, and over the history we have for it it has declined 78.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.0372 per EA |
|---|---|
| All-time high | $10.4335 (Jul 15, 2015) |
| All-time low | $1.6445 (Nov 20, 2024) |
| 52-week high | $2.4682 |
| 52-week low | $1.7078 |
| Median price | $5.5019 |
| Average price | $5.6541 |
| Largest weekly change | +60.0% (Jan 18, 2023) |
| Weeks tracked | 657 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 98% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of PROMETHAZINE 12.5 MG SUPPOS?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 12.5 MG SUPPOS, manufactured by Padagis Israel Pharmaceuticals Ltd, is $2.0372 per EA (NDC 45802075830), effective Jun 24, 2026.
How has the price of PROMETHAZINE 12.5 MG SUPPOS changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE 12.5 MG SUPPOS has declined 78.2%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE 12.5 MG SUPPOS?
Since Nov 28, 2013, the NADAC for PROMETHAZINE 12.5 MG SUPPOS has ranged from a low of $1.6445 (Nov 20, 2024) to a high of $10.4335 (Jul 15, 2015), with a median of $5.5019 per EA.
Are there cheaper alternatives to PROMETHAZINE 12.5 MG SUPPOS?
Yes. 6 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, PROMETHAZINE 12.5 MG TABLET, is $0.0477 per EA — about 98% below PROMETHAZINE 12.5 MG SUPPOS.
Who manufactures PROMETHAZINE 12.5 MG SUPPOS?
PROMETHAZINE 12.5 MG SUPPOS (NDC 45802075830) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.
Related Drugs
Same classification