Product Information

PROMETHAZINE 12.5 MG SUPPOS is a generic product labeled by Camber Pharmaceuticals Inc., priced at $2.0372 per EA under NDC 31722004031. Its NADAC has been published 165 times since May 3, 2023.

PROMETHAZINE 12.5 MG SUPPOS

Promethazine Hydrochloride
$2.0372per EA

Strength

12.5 mg/1

NDC

31722004031

Classification

Generic

Dosage Form

SUPPOSITORY

Route

RECTAL

Last Updated

6/17/2026

Active Ingredients

PROMETHAZINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA216446

On Market Since

11/2/2022

Pharmacological Classes

Phenothiazine
Phenothiazines

Price Statistics

The NADAC for PROMETHAZINE 12.5 MG SUPPOS has been published 165 times since May 3, 2023, and over the history we have for it it has declined 47.1%. The table below summarizes its recorded NADAC range and movement.

Current price$2.0372 per EA
All-time high$4.0268 (Sep 13, 2023)
All-time low$1.6445 (Nov 20, 2024)
52-week high$2.4682
52-week low$1.7078
Median price$2.4241
Average price$2.5764
Largest weekly change-52.5% (Nov 20, 2024)
Weeks tracked165
Tracking sinceMay 3, 2023

Price History

1W

0.0%

1M

+8.4%

3M

+11.2%

6M

+0.5%

1Y

-17.5%

3Y

-39.1%

5Y

N/A

All

-47.1%

Generic Alternatives

The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 98% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROMETHAZINE 12.5 MG SUPPOS?

The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 12.5 MG SUPPOS, manufactured by Camber Pharmaceuticals Inc., is $2.0372 per EA (NDC 31722004031), effective Jun 24, 2026.

How has the price of PROMETHAZINE 12.5 MG SUPPOS changed over time?

Over the history we have for it, the NADAC for PROMETHAZINE 12.5 MG SUPPOS has declined 47.1%. It has been tracked across 165 weekly CMS publications since May 3, 2023.

What are the highest and lowest recorded NADAC prices for PROMETHAZINE 12.5 MG SUPPOS?

Since May 3, 2023, the NADAC for PROMETHAZINE 12.5 MG SUPPOS has ranged from a low of $1.6445 (Nov 20, 2024) to a high of $4.0268 (Sep 13, 2023), with a median of $2.4241 per EA.

Are there cheaper alternatives to PROMETHAZINE 12.5 MG SUPPOS?

Yes. 6 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, PROMETHAZINE 12.5 MG TABLET, is $0.0477 per EA — about 98% below PROMETHAZINE 12.5 MG SUPPOS.

Who manufactures PROMETHAZINE 12.5 MG SUPPOS?

PROMETHAZINE 12.5 MG SUPPOS (NDC 31722004031) is labeled by Camber Pharmaceuticals Inc., and CMS classifies it as a generic product.