Product Information

PROMETHAZINE 50 MG TABLET is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $0.0786 per EA under NDC 53746052201. Its NADAC has been published 198 times since Nov 9, 2022.

FDA first approved this application on Dec 13, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PROMETHAZINE 50 MG TABLET

Promethazine Hydrochloride
$0.0786per EA

Strength

50 mg/1

NDC

53746052201

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

PROMETHAZINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA091179

FDA Approved

12/13/2010

TE Code

AB

On Market Since

6/22/2022

Pharmacological Classes

Phenothiazine
Phenothiazines

Price Statistics

The NADAC for PROMETHAZINE 50 MG TABLET has been published 198 times since Nov 9, 2022, and over the history we have for it it has declined 11.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0786 per EA
All-time high$0.0995 (Jun 14, 2023)
All-time low$0.0696 (Nov 23, 2022)
52-week high$0.0898
52-week low$0.0772
Median price$0.0849
Average price$0.0839
Largest weekly change+35.2% (May 17, 2023)
Weeks tracked198
Tracking sinceNov 9, 2022

Price History

1W

+1.9%

1M

+1.9%

3M

-7.4%

6M

-5.1%

1Y

-12.4%

3Y

+10.7%

5Y

N/A

All

-11.9%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROMETHAZINE 50 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 50 MG TABLET, manufactured by Amneal Pharmaceuticals of New York LLC, is $0.0786 per EA (NDC 53746052201), effective Aug 19, 2026.

How has the price of PROMETHAZINE 50 MG TABLET changed over time?

Over the history we have for it, the NADAC for PROMETHAZINE 50 MG TABLET has declined 11.9%. It has been tracked across 198 weekly CMS publications since Nov 9, 2022.

What are the highest and lowest recorded NADAC prices for PROMETHAZINE 50 MG TABLET?

Since Nov 9, 2022, the NADAC for PROMETHAZINE 50 MG TABLET has ranged from a low of $0.0696 (Nov 23, 2022) to a high of $0.0995 (Jun 14, 2023), with a median of $0.0849 per EA.

Are there cheaper alternatives to PROMETHAZINE 50 MG TABLET?

4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROMETHAZINE 50 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures PROMETHAZINE 50 MG TABLET?

PROMETHAZINE 50 MG TABLET (NDC 53746052201) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.