Product Information
PROMETHAZINE 50 MG TABLET is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $0.0786 per EA under NDC 65162052210. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Dec 13, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162052210
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA091179FDA Approved
12/13/2010
TE Code
AB
On Market Since
3/3/2011
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE 50 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 60.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0786 per EA |
|---|---|
| All-time high | $0.2152 (Feb 12, 2014) |
| All-time low | $0.0689 (Oct 20, 2021) |
| 52-week high | $0.0898 |
| 52-week low | $0.0772 |
| Median price | $0.1056 |
| Average price | $0.1148 |
| Largest weekly change | +48.5% (Aug 19, 2015) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PROMETHAZINE 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 50 MG TABLET, manufactured by Amneal Pharmaceuticals LLC, is $0.0786 per EA (NDC 65162052210), effective Aug 19, 2026.
How has the price of PROMETHAZINE 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE 50 MG TABLET has declined 60.5%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE 50 MG TABLET?
Since Nov 28, 2013, the NADAC for PROMETHAZINE 50 MG TABLET has ranged from a low of $0.0689 (Oct 20, 2021) to a high of $0.2152 (Feb 12, 2014), with a median of $0.1056 per EA.
Are there cheaper alternatives to PROMETHAZINE 50 MG TABLET?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROMETHAZINE 50 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures PROMETHAZINE 50 MG TABLET?
PROMETHAZINE 50 MG TABLET (NDC 65162052210) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.