Product Information
PROMETHAZINE 25 MG TABLET is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $0.0454 per EA under NDC 53746052110. Its NADAC has been published 198 times since Nov 9, 2022.
FDA first approved this application on Dec 13, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Amneal Pharmaceuticals of New York LLCNDC
53746052110
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA091179FDA Approved
12/13/2010
TE Code
AB
On Market Since
6/22/2022
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE 25 MG TABLET has been published 198 times since Nov 9, 2022, and over the history we have for it it has declined 23.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0454 per EA |
|---|---|
| All-time high | $0.0595 (Nov 16, 2022) |
| All-time low | $0.0316 (Nov 20, 2024) |
| 52-week high | $0.0508 |
| 52-week low | $0.0454 |
| Median price | $0.0488 |
| Average price | $0.0478 |
| Largest weekly change | -35.2% (Nov 20, 2024) |
| Weeks tracked | 198 |
| Tracking since | Nov 9, 2022 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PROMETHAZINE 25 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 25 MG TABLET, manufactured by Amneal Pharmaceuticals of New York LLC, is $0.0454 per EA (NDC 53746052110), effective Aug 19, 2026.
How has the price of PROMETHAZINE 25 MG TABLET changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE 25 MG TABLET has declined 23.6%. It has been tracked across 198 weekly CMS publications since Nov 9, 2022.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE 25 MG TABLET?
Since Nov 9, 2022, the NADAC for PROMETHAZINE 25 MG TABLET has ranged from a low of $0.0316 (Nov 20, 2024) to a high of $0.0595 (Nov 16, 2022), with a median of $0.0488 per EA.
Are there cheaper alternatives to PROMETHAZINE 25 MG TABLET?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROMETHAZINE 25 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures PROMETHAZINE 25 MG TABLET?
PROMETHAZINE 25 MG TABLET (NDC 53746052110) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.