Product Information

PROMETHAZINE 25 MG TABLET is a generic product labeled by American Health Packaging, priced at $0.0454 per EA under NDC 68084015501. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Nov 18, 2005. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

PROMETHAZINE 25 MG TABLET

Promethazine Hydrochloride
$0.0454per EA

Strength

25 mg/1

NDC

68084015501

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

PROMETHAZINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA040596

FDA Approved

11/18/2005

TE Code

AB

On Market Since

8/30/2006

Pharmacological Classes

Phenothiazine
Phenothiazines

Price Statistics

The NADAC for PROMETHAZINE 25 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 53.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0454 per EA
All-time high$0.1136 (Feb 12, 2014)
All-time low$0.0316 (Nov 20, 2024)
52-week high$0.0508
52-week low$0.0454
Median price$0.0536
Average price$0.0592
Largest weekly change-35.2% (Nov 20, 2024)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-0.2%

1M

-0.2%

3M

-4.7%

6M

-3.5%

1Y

-10.6%

3Y

-7.9%

5Y

+1.1%

All

-53.4%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROMETHAZINE 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 25 MG TABLET, manufactured by American Health Packaging, is $0.0454 per EA (NDC 68084015501), effective Aug 19, 2026.

How has the price of PROMETHAZINE 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for PROMETHAZINE 25 MG TABLET has declined 53.4%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for PROMETHAZINE 25 MG TABLET?

Since Nov 28, 2013, the NADAC for PROMETHAZINE 25 MG TABLET has ranged from a low of $0.0316 (Nov 20, 2024) to a high of $0.1136 (Feb 12, 2014), with a median of $0.0536 per EA.

Are there cheaper alternatives to PROMETHAZINE 25 MG TABLET?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROMETHAZINE 25 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures PROMETHAZINE 25 MG TABLET?

PROMETHAZINE 25 MG TABLET (NDC 68084015501) is labeled by American Health Packaging, and CMS classifies it as a generic product.