Product Information
PROMETHAZINE 25 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.0454 per EA under NDC 00904730461. Its NADAC has been published 166 times since Jun 21, 2023.
FDA first approved this application on Dec 13, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904730461
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA091179FDA Approved
12/13/2010
TE Code
AB
On Market Since
4/17/2023
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE 25 MG TABLET has been published 166 times since Jun 21, 2023, and over the history we have for it it has declined 9.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0454 per EA |
|---|---|
| All-time high | $0.0517 (Mar 13, 2024) |
| All-time low | $0.0316 (Nov 20, 2024) |
| 52-week high | $0.0508 |
| 52-week low | $0.0454 |
| Median price | $0.0484 |
| Average price | $0.0470 |
| Largest weekly change | -35.2% (Nov 20, 2024) |
| Weeks tracked | 166 |
| Tracking since | Jun 21, 2023 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PROMETHAZINE 25 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE 25 MG TABLET, manufactured by Major Pharmaceuticals, is $0.0454 per EA (NDC 00904730461), effective Aug 19, 2026.
How has the price of PROMETHAZINE 25 MG TABLET changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE 25 MG TABLET has declined 9.6%. It has been tracked across 166 weekly CMS publications since Jun 21, 2023.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE 25 MG TABLET?
Since Jun 21, 2023, the NADAC for PROMETHAZINE 25 MG TABLET has ranged from a low of $0.0316 (Nov 20, 2024) to a high of $0.0517 (Mar 13, 2024), with a median of $0.0484 per EA.
Are there cheaper alternatives to PROMETHAZINE 25 MG TABLET?
6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as PROMETHAZINE 25 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures PROMETHAZINE 25 MG TABLET?
PROMETHAZINE 25 MG TABLET (NDC 00904730461) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.